What does viagra do for a healthy man

But would it regarded as valid reason to quit using Viagra,...The time course of effect was examined in one study, showing an effect for up to 4 hours but the response was diminished compared to 2 hours.

The changes from baseline in scoring on the two end point questions (frequency of successful penetration during sexual activity and maintenance of erections after penetration) were highly statistically significantly in favor of Viagra.The clinical relevance of this finding to men treated with Viagra for ED is not known.The studies that established benefit demonstrated improvements in success rates for sexual intercourse compared with placebo.

Some people may also have ringing in their ears (tinnitus) or dizziness.The type of adverse reactions in flexible-dose studies, which reflect the recommended dosage regimen, was similar to that for fixed-dose studies.Figure 4: Mean Standing Systolic Blood Pressure Change from Baseline.

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Of the total number of subjects in clinical studies of Viagra, 18% were 65 years and older, while 2% were 75 years and older.After patients have taken Viagra, it is unknown when nitrates, if necessary, can be safely administered.Co-administration of erythromycin, a moderate CYP3A4 inhibitor, resulted in a 160% and 182% increases in sildenafil C max and AUC, respectively.Sildenafil was negative in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro human lymphocytes and in vivo mouse micronucleus assays to detect clastogenicity.Results with all doses have been pooled, but scores showed greater improvement at the 50 and 100 mg doses than at 25 mg.Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.This finding is consistent with the inhibition of PDE6, which is involved in phototransduction in the retina.

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You are now leaving VIAGRA.com to enter a website neither owned nor operated by Pfizer.The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse any of the products or services.Stronger CYP3A4 inhibitors such as ketoconazole or itraconazole could be expected to have greater effects than seen with saquinavir.Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

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Especially tell your healthcare provider if you take any of the following.

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Our Viagra Side Effects Drug Center provides a comprehensive view of available drug information on the potential side.These events, which may be accompanied by tinnitus and dizziness, have been reported in temporal association to the intake of PDE5 inhibitors, including Viagra.

Sildenafil: MedlinePlus Drug Information

If a subject did not successfully complete this first dosing period, he was discontinued from the study.

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VIAGRA helps guys with erectile dysfunction get and keep an erection.

Nervous: seizure, seizure recurrence, anxiety, and transient global amnesia.Abnormal Vision: Mild and transient, predominantly color tinge to vision, but also increased sensitivity to light or blurred vision.One patient discontinued the study prematurely due to an adverse event of hypotension following dosing with Viagra 50 mg.

Patients should always ask their doctors for medical advice about adverse events.Studies in vitro have shown that sildenafil is selective for PDE5.In a study of healthy male volunteers, sildenafil (100 mg) did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates.

A sudden drop in blood pressure can cause you to feel dizzy, faint, or have a heart attack or stroke.Viagra may affect the way other medicines work, and other medicines may affect the way Viagra works causing side effects.When vasodilators are used in combination, an additive effect on blood pressure may occur.Scroll or Click for Important Safety Information and Indication.The AUC of the active metabolite, N-desmethyl sildenafil, was increased 62% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers.For the 20 subjects who received Viagra 100 mg and matching placebo, the placebo-subtracted mean maximum decreases from baseline (95% CI) in systolic blood pressure were as follows.REVATIO is used to treat a rare disease called pulmonary arterial hypertension (PAH).Men with untreated ED had relatively low baseline scores for all aspects of sexual function measured (again using a 5-point scale) in the IIEF.When Viagra is taken with a high fat meal, the rate of absorption is reduced, with a mean delay in T max of 60 minutes and a mean reduction in C max of 29%.

Ask your doctor if your heart is healthy enough to handle the extra strain of having sex.For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity.